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噻替派或卡介苗等膀胱内灌注治疗及预防膀胱癌术后复发158例报告

THE RESULTS OF TREATM NT AND PREVENT RECURRENCE OF POSTOPERATIVE INTRAVESICAL BCG OR THIO-TEPA THERAPY OF BLADDER CANCER
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摘要 膀胱癌行保留膀胱的手术后,用噻替派或卡介苗等药物行膀胱内灌注,以预防复发及治疗残余癌共158例。随访6月~4年半,结果肿瘤复发率为:卡介苗组11.29%,噻替派组28.16%,未预防灌注组43.47%。卡介苗治疗残余癌有效率为60%。对部分病例于灌注前后还进行了免疫观测。 158 cases of bladder carcinoma were treated by intravesical application of BCG or Thio -tepa etc, to prevent postoperative recmence and to treat residual tu mors. The results of treatment were as follows : The recurrence rate was 11.29% in BCG group, 28.16% in Thiotepa group and 43.37% in control group. The immunologic studies of the patients before and after the treatment showed, that there is no parallelism between the therapeutic effect of BCG perfusion and the changes of immunologic parameters.
出处 《癌症》 SCIE CAS CSCD 北大核心 1990年第6期488-490,共3页 Chinese Journal of Cancer
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