摘要
144例Ⅱb期宫颈癌患者分为6组,a组23例因盆腔淋巴结未检出癌灶仪行根治手术。b组21例因盆腔淋巴结有癌灶,术后加体外放疗。c组36例、d组14例系化疗加根治术治疗,化疗多是经动脉灌注5-Fu及噻替派,无盆腔淋巴结转移者仅化疗—疗程,阳性者化疗二疗程。e组36例、f组14例为对照组接受标准放疗。6组5年生存率分别为86.9%、76.2%、80.5%、50.0%、61.1%和42.9%。
144 patients with cervical carcinoma at stage Ⅱb (FIGO) were treated with surgery or radiation orfsurgery and radiation or chemotherapy and surgery. Among 144 cases 61 (42.4%) were between 50-59 years old, 63 cases developed infiltrative-type. 23 cases received operation only because no cancer could be seen in their pelvic lymph nodes (A), 21 patients were treated with surgery plus external radiotherapy because of positive pelvic lymph node(B). Group C including 36 cases underwent chemotherapy via a catheter from inferier epigastric artery to lower aorta, then surgery was delive-ried with inserting of tubes through uterine artery to hypogas-tric artery. 41% of 36 cases occr-ured positive node. Postoperative chemotherapy was given viacatheters at hypogastric artery. Cancers in group D had infiltra-tive parametrium in cord-like reaching pelvic wall and 9 of 14 patients developed positive node. They received the same therapy as that in group C. When the node showed positive the patient underwent 2 cycles of chemotherapy postoperatively. Most cases were used 5Fu or thio-Tepa.Group E and C,they had the same pelvic condition,and so did group F and D. Cases in group E(n=36) and F (n= 14 ) received standard radiotherapy. The 5-year survival rate of 6 groups was 86.9%, 76.2 %,80.5%, 50.0%, 61.1%, and 42.9% respectively.
出处
《现代妇产科进展》
CSCD
1995年第2期131-132,共2页
Progress in Obstetrics and Gynecology
关键词
子宫颈肿瘤
药物疗法
放射疗法
治疗
Cervical neoplasms
Drug therapy
Radiotherapy
5-year survival