摘要
本文以肉瘤S^(180)、艾氏腹水癌为模型,研究了SPA、SAC和SAW体内注射的治疗方式对疗效的影响。结果表明,纯品SPA对腹水型肿瘤无效,菌体SAC和SAW则效果显著,三者的治疗途径与肿瘤生长部位接近或相同时效果较好,SAC的治疗剂量与疗效有关。
In this paper, the influence of therapeutic manner with purifiedstaphylococcal protein A (SPA), Staphylococcus Aureus Cowan I(SAC)and Stap-hylocbccus Aureus wood 46(SAW) on in vivo the antitumor effects were investigated by using two tumor models, Sarcoma 180(S180)and Ehrlich Ascites Cancer (EAC). The results indicated that SPA did not show any antitumor effect on the ascitic tumor, but both SAC and SAW had remarkable effects. The therapeutic effects were better, if the route of administration was closed to or coincident with the location of tumors. The therapeutic effect of SAC was related to the dose used.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1990年第1期33-36,共4页
Chinese Journal of Cancer
基金
国家"七五"肿瘤攻关项目
