摘要
目的研究翻白草对糖尿病大鼠胰岛B细胞的作用。方法采用四氧嘧啶建立糖尿病大鼠模型,自造模成功后,灌胃给予翻白草水煎液,连续给药4周,常规取材、固定、切片,采用醛品红法染色,镜下观察。结果翻白草组大鼠胰岛边界清楚,B细胞数量较正常对照组略有减少,但较模型对照组密度高,细胞结构完整,无肿胀坏死现象。结论翻白草能有效保护胰岛B细胞。
Objective: The research turns over the function of Potentilla discolour bunge(PDB) on the pancreatic islet B cells of the DM rat. Methods: The rats were done into diabetic model by injected alloxan, and then the rats were perfused a stomach with PDB decoction for 4 weeks continuously. The pancreatic islet B cells were stained with aldehyde fuchsine. Results:It shows that the boundary of pancreatic islet of the PDB group rats is clear, that the cell structure is complete,and that there is no the putrescence phenomenon. Conclusion; PDB can protect effectively the pancreatic islet B cells.
出处
《湖北中医学院学报》
2005年第3期28-29,共2页
Journal of Hubei College of Traditional Chinese Medicine
基金
湖北省教育厅重点科研项目(编号:2004X080)
关键词
翻白草
糖尿病
胰岛
Potentilla discolor bunge
Diabetes mellitus
Islets of pancreas