摘要
目的:监测我院病房分离的100株革兰阴性杆菌对12种抗生素的耐药率,以指导临床用药。方法:采用E test药敏试验测定我院分离的100株革兰阴性杆菌对12种抗生素的最低抑菌浓度(M IC)。结果:这12种抗生素中总耐药率最低的是亚胺培南(7%),头孢吡肟(13%),舒普深(14%),阿米卡星(14%);49株大肠埃希菌及肺炎克雷伯菌中,超广普β-内酰胺酶的发生率为43%;大肠杆菌对环丙沙星的耐药率高达76.5%;大肠埃希菌,肠杆菌属,不动杆菌,克雷伯菌属对亚胺培南的耐药率小于等于5.9%。结论:亚胺培南,头孢吡肟,舒普深,阿米卡星对革兰阴性杆菌的耐药率最低。
Objective： To investigate the resistangt rate of gram-negative bacilli isolated from wards of West China Hospital to 12 antibiotics. Method： Etest was used to detect the minimal inhibition concentration of 100 gram-negative bacilli isolated from West China Hospital against 12 antibiotics. Results： In 12 antibiotics, Imipenem, Cefepime, Cefopreazone sodium/Sulbactam, Amikaein had the lowest overall resistant rates of 7%, 13%, 14%, 14% respectively ,The prevalence of extended spectrum β-lactamase was 43% in 49 E, coli and Klebs. pneumoniae strains. 76.5% E. coil strains were resistant to Ciprofloxacino The resistant rates of E. coil, Enterobcter, Aeinetobaeter, Klebsiella. spp to Imipenem was less than 5.9%. Conclusion： Imipenem, Cefepime, Cefopreazone sodium/Sulbactam, Amikaein were the most effective antimicrobial agents to all detected gram-negative bacilli.
出处
《四川生理科学杂志》
2005年第4期161-164,共4页
Sichuan Journal of Physiological Sciences
