摘要
目的研究红细胞在脑出血后脑水肿形成中的作用。方法向大鼠尾状核分别注入浓缩红细胞(PRBC)、溶解红细胞(LRBC)及不同浓度的大鼠血红蛋白(Hb),并比较鼠脑不同部位脑水肿形成的特点。结果红细胞对脑水肿的影响要在脑出血后第3d,其水肿的严重程度与Hb的浓度呈正相关。结论红细胞对脑出血后脑水肿形成的影响主要在脑出血后第3d,可能与红细胞溶解释放血红蛋白有关。
Objective To study the effect of erythrecytes on the formation of brain edema after intracerebral hemorrhage in rats, Methods The rat＇s packed red blood cells, lysed red blood cells and hemoglobins in different concentrations were injected respectively into the rat＇s caudate nucleus. The changes of edema in various regions of the rat＇s brain were measured, Results The main effect of erythrocytes on edema was in the third day after intracerebral hemorrhage. There was a positive correlation between the severity of edema and the concentration of hemoglobin. Conclusion The effect of erythrocytes on edema is mainly at the third day after intracerebral hemorrhage, as is probably relevant to the hemoglobin released by the lysed red blood cells.
出处
《中国实用神经疾病杂志》
2006年第1期17-19,共3页
Chinese Journal of Practical Nervous Diseases
关键词
红细胞
脑出血
脑水肿
红血蛋白
Erythrocyte
Intracerebral hemorrhage
Brain edema
Hemoglobin
