摘要
本文比较正常肺组织和肺癌多克隆角蛋白免疫组化标记结果。10例围产儿尸检肺和31例癌旁组织的正常支气管及较大分支均阳性,程度由近端向末梢逐渐递减。支气管腺体中,浆液性腺泡阳性。鳞癌39例,每例均可查见数量不等的强阳性细胞;这对Ⅲ级鳞癌的诊断很有价值。腺癌20例,呈中度或弱阳性反应,分布较均匀;腺样结构和粘液分泌仍为诊断依据。差分化癌17例和小细胞癌6例以弱阳性为主。还结合文献进行讨论。
This retrospective study evaluated the us; of immunoperoxidase stain for keratin in the diagnosis of lung cancer. It was performed on paraffin sections from 82 lung neoplasms, and the results were compared with those of the normal bronchus. Strong staining for keratin was evident in all squamous cell carcinomas (39 cases) . This reaction was particularly helpful in identifying squamous differentiation in poorly differentiated area of the tumour. Intermediate or weak positive stain could be seen in adenocarcinomas ( 20 cases ) , and weak positive stain in poorly differentiated carcinoma (13 of 17 cases) and small cell carcinoma (4 of 6 cases ) .
出处
《蚌埠医学院学报》
CAS
1989年第2期150-153,共4页
Journal of Bengbu Medical College
关键词
肺癌
角蛋白
免疫组化
lung neoplasm
keratin
iminunobistochemistry
