摘要
目的 骨肉瘤合并明显移位病理性骨折保肢治疗的近期疗效观察。方法2002年10月～2003年1月，2例骨肉瘤合并明显病理性骨折患者，行动脉化疗泵埋置、肿瘤活检术后即开始化疗，5次化疗后行人工关节假体置换保肢手术，术后继续化疗。结果 术后无感染，假体无松动，患肢功能恢复良好。分别获随访24个月和21个月，肿瘤无复发、转移。结论 原发性骨肉瘤合并病理性骨折患者在有效、敏感的化疗及综合治疗下，保肢治疗并非其禁忌证。
Objective To investigate the effect of limb salvage on treating osteosarcoma with pathological fracture. Methods From October 2002 to January 2003, 2 cases of osteosarcoma with pathological fracture were treated by limb salvage. Intra-arterial chemotherapy was given by subcutaneous implantable delivery system with caffeine. Replacement with prosthesis was performed after 5 times of chemotherapy. Results Two patients were followed up for twenty-four months and 21 months respectively. No infection, aseptic loosening, local recurrence or metastasis occurred, and function recovery of joints was satisfactory. Conclusion Limb salvage can be considered in condition that primary osteosarcoma with pathological fracture can be treated by effective and comprehensive chemotherapy.
出处
《中国修复重建外科杂志》
CAS
CSCD
北大核心
2006年第1期30-32,共3页
Chinese Journal of Reparative and Reconstructive Surgery
关键词
骨肉瘤
病理骨折
保肢治疗
Osteosarcoma Pathological fracture Limb salvage
