摘要
目的提高骨髓中组织胞浆菌病、黑热病、马尔尼菲青霉菌病、弓形虫病及新型隐球菌病病原体的诊断和鉴别诊断水平。方法分析7例组织胞浆菌病,1例黑热病,1例马尔尼菲青霉菌病,2例弓形虫病和3例新型隐球菌病的临床特征及骨髓形态。结果骨髓中组织胞浆菌呈卵圆形,菌体周围有一圈不着色区;杜利小体形状与其相似,但体内可见深红色的动基体;腊肠形的细胞和横隔是马尔尼菲青霉菌的特征;弓形虫外型似香蕉,体积稍大;新型隐球菌为较大圆形孢子,有一肥厚的荚膜。结论骨髓中病原体的形态检查对疾病的诊断起重要作用。
Objective To facilitate the diagnosis of histoplasmosis, kala-azar, penicilliosis mameffei, toxoplasmosis and cryptococcosis with the help of bone marrow morphology. Method The clinical features and bone marrow cytomorphology in 7 cases of histoplasmosis, 1 case of kela-azar, 1 case of penicilliosis marneffei ,2 cases of toxoplasmosis and 3 cases of cryptococcosis were studied. Results In the bone marrow examination, the form of histoplasma capsule was ovoid with a colorless circle. The morphology of Leishmania donovani was similar to that of histoplasma capsule except that there were terkinetoplasts present in the former. Sausage form and central cross wall were signs of Penicillium marneffei. Toxoplasma gondii looked like a banana and cryptococcus neoformans was larger than the others and had a thick capsule. Conclusion The examination of bone marrow is important to the diagnosis of these rare infectious diseases.
出处
《中华内科杂志》
CAS
CSCD
北大核心
2005年第12期902-905,共4页
Chinese Journal of Internal Medicine
关键词
组织胞浆菌病
利什曼病
内脏
隐球菌病
弓形虫病
骨髓检查
Histoplasmosis
Leishmanisis, visceral
Cryptococcosis
Toxoplasmosis
Bone marrow examination