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数字影像学检查在大鼠肺癌模型中的应用

Digital Image Analysis in Lung Cancer Model of Rats
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摘要 目的探讨数字影像在大鼠肺癌模型中的应用。方法将140只经左肺叶灌注含敛癌质碘油的大鼠随机分为2组:实验组84只,用philips V5000 DSA机摄胸部照片;对照组56只,使用岛津UD 150L-30E X光机摄胸片。每组均于灌注后1、14、30~42 d检查肺部3次,共计摄片420次。每组从制模成功的大鼠中随机抽取30只,最后一次摄片时测量病变大小,并与病理结果对照。结果实验组大鼠肺部图像中,甲、乙、丙级片分别为89.3%、10.7%、0.0%;对照组分别为71.4%、23.2%、5.4%。病变定位正确率两者均为100%,病变大小测量误差率:实验组0级56.6%、I级40%;对照组0级33.3%、I级36.7%。结论数字影像检查大鼠肺癌比常规X线摄片清晰、准确,可用于肺癌的检查和辅助诊断。 Objective To evaluate the implication of digital image in lung cancer model of rats and the quality of radiology on digital image. Methods 140 Wistar rats were perfused with tumor-inducilble iodinatedoil in left pulmonary by digital image and quality of the photo was compared with that of the other 56 rats'conventional radiology. Results The graphic quality in digital image group was better than that of conventional radiology which the rats ofA,Band C grade graphic quality was 39.3%, 10.7% and 0% respectively vs 71.4%,23.2%and 5.4% in conventional group. Conclusion digital image is superior to the conventional radiology in graphic quality for evaluating rats's model of lung cancer.
出处 《医学新知》 CAS 2005年第4期35-36,F0003,共3页 New Medicine
基金 湖北省科技厅"十五"攻关计划资助 课题号20001P1804
关键词 数字影像学 大鼠 肺癌 动物模型 X线摄片 图片质量 Lung cancer Wistar rats Digital image
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