摘要
探讨甲状腺功能亢进症(甲亢)初诊患者肝功能异常的发生率、临床特点及相关因素。将428例甲亢患者根据肝功能是否异常分为两组,分析其临床表现、肝功能指标与血清甲状腺激素水平以及甲状腺自身抗体的水平的关系。初诊甲亢患者肝功能异常的发生率为30．1％,肝功能损害最常见的是碱性磷酸酶(ALP)、丙氨酸氨基转移酶(ALT)增高,其甲状腺激素水平显著高于无肝功能异常者。而TSH、甲状腺微粒体抗体(TMA)、甲状腺球蛋白抗体(TGA)则无明显差异。甲亢初诊患者合并肝功能异常较常见,肝功能损害以ALP、ALT增高为最常见,且与甲状腺激素水平关系密切。
To study the prevalence, the clinical characteristics and the possible risk factors of hepatic dysfunction in newly diagnosed hyperthyroid patients. 428 newly diagnosed hyperthyroid patients were present or not, the clinical manifestation, liver function tests, serum thyroid hormone and thyroid auto - antibodies were reexamined in these patients. The prevalence of hepatic dysfunction newly diagnosed hyperthyroid patients was 30.1%, increased ALP ,ALT were the most familiar abnormal hepatic function parameters. In the patients with hepatic dysfunction, the serum thyroid hormone levels were significantly higher. There wer no significant difference in the serum TSH, TMA, TGA. Hepatic dysfunction in newly diagnosed hyperthyroid patients is common, increased ALP,ALT are the most familiar abnormal hepatic function parameters, and there is correlation between the elevation of liver function tests and the thyroid hormone levels.
出处
《临床肝胆病杂志》
CAS
2005年第6期350-351,共2页
Journal of Clinical Hepatology
