摘要
大量研究表明,血小板功能异常在缺血性脑血管病的发病机制中扮演着相当重要的角色。血小板黏附和聚集试验能检测血小板的黏附性和聚集性,缺血性脑血管病患者血浆β-血小板球蛋白、血小板第4因子、血栓素B2、6-酮-前列腺素F1α、血小板活化因子和P-选择素水平可反映血小板是否处于活化状态。检测各种血小板功能标志物,有助于了解血小板的功能状态,对缺血性脑血管病的诊断、预防、治疗和预后判断均有重要意义。
A great number of studies have suggested that platelet dysfunction plays an important role in the pathogenesis of ischemic cerebrovascular diseases, The platelet adhesion and aggregation tests can detect its adhesiveness and cohesiveness. Plasma β-thromboglobulin, platelet factor 4, thromboxane B2, 6-keto-PGF1 α, platelet-activating factor, and P-selectin levels in patients with ischemic cerebrovascular disease may reflect whether platelet is in an active state. The determination of the markers of platelet function is helpful to understand the functional sta- res of platelet, and it has important significance in the diagnosis, prevention, treatment and prediction of prognosis for ischemic cerebrovascular diseases.
出处
《国外医学（脑血管疾病分册）》
2005年第10期779-782,共4页
Foreign Medical Sciences Cerebrovascular Diseases
