摘要
目的探讨疏血通注射液对急性脑梗死病人的神经功能及6-酮-前列腺素(6-keto-PGF1α)、血栓素B2(TXB2)的影响。方法60例急性脑梗死病人随机分为两组,对照组30例进行常规基础治疗,治疗组30例在常规基础治疗的同时给予疏血通注射液静脉输注,比较两组治疗前后病人神经功能评分、临床疗效及TXB2、6-keto-PGF1α的变化。结果治疗组神经功能评分明显减少、临床症状显著好转,TXB2显著降低、6-keto-PGF1α显著升高,与对照组比较有统计学意义。结论疏血通注射液可调节TXB2/6-keto-PGF1α的平衡,抑制血小板活化,改善临床疗效。
Objective To Investigate the influence of Shuxuetong Injection on therapeutic effect and the change of TXB2,6 - keto- PGF1α in patients （pts） with acute cerebral infarction. Methods Sixty pts with acute cerebral infarction were randomly divided into two groups. The pts in control group were treated with conventional therapy, The pts in Shuxuetong group were treated with conventional therapy and Shuxuetong Injection. The neurologic function score, Clinical symptom and TXB2,6 - keto- PGF1α were bserved pre- and post - therapy. Results To compared with the control group, there was remarkable difference on the decrease of neurologic function score and TXB2, The 6 - keto - PC-F1α increased and the clinical symptom improved in the Shuxuetong group. Conclusion Shuxuetong Injection could regulate the balance of TXB2/6 - keto - PG F1α, inhibit activity of platelet and improve clinical neurologic function significantly,
出处
《中西医结合心脑血管病杂志》
2006年第5期394-395,共2页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
