摘要
目的:探讨精神分裂症患者认知障碍的情况。方法:对99例符合CCMD-3精神分裂症诊断标准的精神分裂症病人和38例正常人实施威斯康星卡片分类测试(WCST),并对其中28例经过8周抗精神病药物治疗的患者进行治疗前后对比,观察BPRS评分与WCST变化情况。结果:精神分裂症患者WCST的总测验次数,持续错误数和随机错误数与年龄、BPRS总分正相关(P<0.01),正确数和分类数与年龄、BPRS评分成负相关(P<0.05);WCST两组间在性别及文化程度上差异无显著性,对28例患者治疗前后比较,显示WCST随病情的好转而改善。而治疗前后WCST的总测验次数,持续错误数,随机错误数的减分率与BPRS减分率正相关(P<0.05)。结论:精神分裂症患者存在认知功能损害。
Objective： To study cognize function about schizophrene. Methods：Both 99 schizophrenes and 38 ordinary persons were tested with WCST BPRS and WCST of 28 schizophrenes were compared at treatment before and after. Results： total examine times and continue mistake times and random mistake times is positive correlation with ages and total BPRS（ P 〈 0.01 ）. Right times and number of categories is negative correlation with ages and total BPRS（ P 〈0. 05）. Conclusions：cpgnize function of schizophrenes had been damaged.
出处
《中国民康医学》
2005年第12期735-736,共2页
Medical Journal of Chinese People’s Health
