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颈内动脉灌注顺铂和阿霉素治疗脑肿瘤的临床观察

The clinical study of carotis internal arterial infusion of cis Platinum and Adriamycin in the treatment of brain tumor.
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摘要 本文报道了经颈内动脉灌注顺铂和阿霉素治疗脑肿瘤27例(胶质瘤22例,恶性淋巴瘤2例,转移性肿瘤3例)。在疗前和疗后2个月用CT检查比较肿瘤体积变化。结果:22例胶质瘤有7例缩小50~80%,有效率31.83%;2例恶性淋巴瘤分别缩小76.07%和48.90%;转移性肿瘤2例肿瘤完全消失,另1例缩小62.62%。全部患者均无严重视网膜及神经毒性反应。认为颈内动脉灌注顺铂和阿霉素对颅内转移性肿瘤和恶性淋巴瘤疗效满意。 patients were treated by carotis internal arterial infusion of cis platinum and adriamycin.22 of them were glioma,2 of them were malignant lymphoma and 3 of them were brain metastases.CT scan was implemented before chemotherapy and two moths after chemotherapy,in order to observe the change of the tumor.In the glioma group seven tumors size decreased 50~58%,two malignant lymphoma the tumor size decreased 76.07% and 48.9% respectively.Among the cases of the brain metastases,the tumor disappeeared in two cases and reduced to 62.62% in another case.There were no symptome of neurotoxicity and vision decrease in those patients.The result of carotis internal arterial infusion of cis platinum and adriamycin on glioma was not very effective,but was good on brain metastase and malignant lymphoma.
出处 《临床神经病学杂志》 CAS 1996年第3期155-158,共4页 Journal of Clinical Neurology
关键词 颈内动脉 脑肿瘤 药物疗法 Carotis internal arterial Chemotherapy Brain tumor
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  • 1王振宇,中华神经外科杂志,1987年,3卷,157页

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