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内镜下粘膜内注墨法标记胃癌前病变方法

The Method for Marking Gastric Precancerous Lesions by Endoscopic India Ink Injection
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摘要 为了有助于胃癌前病变随访中定位活检.我们采用内镜下粘膜内注墨法标记43例胃癌前病变,探讨了注墨法注射剂的制备和使用方法.发现用生理盐水按1:10和1:100比例稀释印度墨水,可减少墨水对组织的刺激,并可保证墨点标记清晰持久.墨点标记存留时间达16±8月(11~25月).粘膜内墨点清晰,大多数呈点状(38/43),不影响病变粘膜观察.注墨处无增生和坏死等组织反应,碳素颗粒大多数局限在粘膜固有层中(12/14). To facilitate the relocation of biopsy site in follow-up endoscopic examination for gastric precancerous lesions, tattooing of gastric intramucosa was used to mark the lesions in 43 patients by endoscopic India ink injection. We found that if India ink was diluted 1:10 or 1:100 with 0.9% saline solution, the tissure reaction to injected ink could be dismished. The intramucosal injection of sterilized India ink produced a zone of black coloration that is grossly visible and could be preserved 16± 8 months (11-25 months). Most of tattoos appeared dots (38/43), which did not affect the observation at follow-up endoscopy. There were not distinct inflammation, proliferation and necrosis in the tattoo site in which most of carbon particales( 12/14) were found to located only in the mucosa.
出处 《临床消化病杂志》 1996年第2期65-67,共3页 Chinese Journal of Clinical Gastroenterology
基金 安徽省卫生厅医学重点科研课题资助项目
关键词 印度墨水 注墨法 胃癌前病变 India ink Tattooing Gastric precancerous lesions
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