摘要
目的:观察围手术期免疫营养对梗阻性黄疸(OJ)病人的治疗效果。方法:将46例OJ病人随机分为试验组(免疫营养,含ω-3脂肪酸,n=21)和对照组(普通营养,n=25)。围手术期进行等热量、等氮量的营养支持,手术前1天、术后3天、10天测定T细胞亚群、淋巴细胞总数、血清清蛋白、胆红素。统计感染并发症的发生率。结果:与对照组比较,试验组T细胞亚群绝对数、淋巴细胞总数明显回升,感染并发症发生率下降(P<0.05),血清清蛋白、胆红素差异无显著性意义(P>0.05)。结论:OJ病人围手术期应用免疫营养支持能改善病人的营养状况,提升免疫功能,改善预后。
Objective ： To observe the therapy effect of immunonutrition in obstructive jaundice （ OJ） patients during perioperative period. Methods： 46 patients with OJ were randomized into two groups：research group（ n = 21, given immunonutrition） and control group （ n = 25, given regular nutrition）. Each was given an isocaloric and isonitrogenous diet during perioperative period. The variables （ T-cell subsets, total lymphocytes,albumin ,blood bilirubin） were measured before and day 3 and 10 after operation. The rate of infectious complications was also recorded. Results ： Compared with the control group,the T-cell subsets level and total lymphocytes were higher and the rate of infectious complications was lower（ P 〈 0.05 ） in research group. Albumin and bilirubin were not obviously different between two groups. Conclusion ： Immunonutrition during perioperative period can improve nutritional condition and immune function in OJ patients.
出处
《肠外与肠内营养》
CAS
2005年第6期338-340,共3页
Parenteral & Enteral Nutrition
基金
浙江省医药卫生科学研究基金资助项目(批准号:2004B192)
关键词
梗阻性黄疸
免疫营养
T细胞亚群
Obstructive jaundice
Immunonutrition
T-cell subsets
