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肝细胞生长因子在内皮细胞和高血压中的研究进展 被引量：3

Effect of Hepatocyte Growth Factor in Endothelial Cell and Hypertension
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摘要 肝细胞生长因子(HGF)是一种内皮细胞特异性生长因子,促进内皮细胞的增殖和移行,抑制内皮细胞的凋亡。高血压患者血清HGF水平与血压高低、靶器官损害程度和血压节律异常有关,可能成为反映高血压内皮功能不全的一个新指标。一些药物能降低高血压患者血清HGF水平。 Hepatocyte growth factor is an endothelium-specific growth factor that stimulates proliferation and migration of endothelial cells and inhibits apoptotic actions of them. Serum HGF concentration in hypertensive patients is associated with the levels of blood pressure, the degree of target organ damage and the abnormal circadian rhythm of blood pressure, and may be a new index of endothelial dysfunction. Some drugs can decrease serum HGF concentration in hypertensive patients.
作者 胡泽平 王邦宁
机构地区 安徽医科大学第一附属医院心内科一病区CCU
出处 《心血管病学进展》 CAS 2005年第6期595-598,共4页 Advances in Cardiovascular Diseases
关键词 肝细胞生长因子 内皮细胞 高血压 Hepatocyte growth factor Endothelial cell Hypertension
分类号 R544.1 [医药卫生—心血管疾病]
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参考文献5

二级参考文献38

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共引文献21

同被引文献23

  • 1陈建英,陈晓于,黄石安,陈灿,李果明,陈亮波.原发性高血压患者肝细胞生长因子、血管紧张素Ⅱ、内皮素的变化及苯那普利的干预作用[J].中国循环杂志,2004,19(4):283-285. 被引量：8
  • 2欧阳珊,乔福元.妊娠期高血压疾病胎盘肝细胞生长因子表达与滋养细胞凋亡[J].中华围产医学杂志,2006,9(4):233-235. 被引量：4
  • 3钟文筠,周君桂,庞战军.妊娠高血压综合征胎盘组织中细胞因子基因的表达[J].中国妇幼保健,2007,22(6):818-822. 被引量：1
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心血管病学进展
2005年 第6期

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