摘要
目的:根据NCCLSEP9-A2文件标准比较我室两个生化检测系统测定结果之间的一致性并评估其一致性的可接受性。方法:根据美国临床实验室标准化委员会(NCCLS)EP9-A2文件标准,每天取患者样本8份,浓度尽可能分布于分析检测范围(AMR)的高、中、低内,分别在我室常规应用的两台全自动生化分析仪Olympus5400和Olympus2700上测定15项常规生化指标,不连续5天测定,结果进行相关分析。根据直线方程计算在某医学决定水平处的预期偏倚(^BC)和预期偏倚的95%可信区间,并判断偏倚是否可以接受。结果:除血糖测定在医学决定水平2.5mmol/L处偏倚不可接受,其余常规生化指标测定结果预期偏倚均在要求范围内。结论:两个型号的奥林巴斯全自动生化分析仪对15项生化指标分析能得到一致的检测结果。
Objective： To evaluate the bias and acceptability of the bias from two analytical systems. Method： According to the NCCLS EP9 - A Second Edition document, 8 specimens per day were collected to assay 15 routine biochemical tests by utilizing two types Olympus biochemical autoanalyser at discontiguous five days. M1 results were sheeted to accumulate the linearity equation and the relativity coeffieient. The 95 % confidence interval of Bc （bias at medical decision level X） were calculated in order to estimate acceptability of the bias. Results： Except bias of glucose is unacceptable at medical decision level 2.5 mmol/L, the bias of rest routine biochemical tests ean be accepted between two analytical systems. Conclusions： Result indicated that two types Olympus biochemical autoanalyser determined fresh patient serum to pruduce consistency results in most routine biochemical tests.
出处
《华西医学》
CAS
2005年第4期673-674,共2页
West China Medical Journal
