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^(131)I联合强的松治疗中-重度Graves′眼病疗效观察 被引量:2

Clinical Observation of Therpeutic Effect of ^(131)I and Prednisone on Graves′Ophthalmopathy
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摘要 目的:观察131I加强的松治疗G raves′眼病(GO)的临床疗效。方法:对108例中-重度患者随机分为两组,Ⅰ采用单纯131I治疗,Ⅱ采用131I加强的松。治疗后分别对两组眼病疗效进行对比分析。结果:108例GO患者均经1次131I治疗,两组共治愈87例(81.0%),Ⅰ组50例眼病患者中,眼病改善20例(40.0%),无变化22例(44.0%),恶化8例(16.0%);Ⅱ组58例患者中,眼病改善38例(65.5%),无变化17例(29.3%),恶化3例(5.1%)。两组比较差异有显著性(P<0.05)。结论:GO疗效与甲亢疗效有关,131I加强的松治疗的GO疗效明显高于单纯131I治疗。 Objiective:To Observe the clinical effect of ^131I and prednisone on Graves' ophthalmopathy(GO). Methods : 108 patients with moderate or severe GO were randomly divided in two groups. 50 cases in group Ⅰ were treated with ^131I only. 58 cases in group Ⅱ were treated with ^131I and prednisone. The therapeutic effect in two groups was used to compare and analyse, Resuit: 87 (81. 0%) cases of two groups were effectively cured once. The remarkably efftive outcome ,no chang and worsen of orbitopathy disease was observed in 38(65.5% ), 17 (29.3% ) and 3(5.1% )cases in prednisone and ^131I treanted group and 20(40%),22(44.0%) and 8(16.0%)cases in ^131I treated group. There were significant differences in both groups. Conclusion :Therapeutic effect of Go is in connection with therapeutic effect of hyperthyroidism. The effect of ^131I and prednisone is more remarkably effrtiver than ^131I in treatment of GO.
出处 《中国误诊学杂志》 CAS 2005年第15期2801-2802,共2页 Chinese Journal of Misdiagnostics
关键词 格雷夫斯病/药物疗法 碘放射性同位素/治疗应用 泼尼松/治疗应用 ^131I治疗 强的松治疗 GRAVES 眼病患者 疗效观察 重度 联合 Graves'disease/drug therapy Iodine radioisotopes/therapeutic use Prednisone/therapeutic use
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  • 1陈跃,邱陵,张春银,龙水清,甘西伦.^(131)碘配合强的松治疗Graves眼病的疗效分析[J].泸州医学院学报,2005,28(4):334-336. 被引量:2
  • 2王光琳,鞠海兵,马黎明,李江城,邱苏云.强的松联合^(131)I治疗Graves眼病临床观察[J].西南军医,2007,9(3):28-29. 被引量:1
  • 3王洁,王鑫,魏庆芳,秦丽阳.^131碘配合强的松治疗Graves眼病的疗效观察[J].中国地方病学杂志,2007,26(4):459-459. 被引量:3
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