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老年脑卒中后肢体瘫痪患者血清IL-4、IL-6、IL-10水平变化及意义 被引量:2

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摘要 目的:探讨细胞因子在老年脑卒中后肢体瘫痪患者骨质疏松症发病机制中的作用。方法:采用放射免疫分析法检测170例老年脑卒中后肢体瘫痪患者血清白细胞介素4(IL-4)、白细胞介素6(IL-6)、白细胞介素10(IL-10)的水平,采用美国Lunar公司生产的DEXA双能X线骨密度仪测量患侧股骨颈骨密度。结果:老年脑卒中后肢体瘫痪患者发病1年后,患者骨吸收指标IL-4、IL-6水平增高,骨形成指标IL-10表达降低,均有极显著性差异(P<0.001).患者患侧股骨颈骨密度减低有极显著性差异(P<0.001)。结论:IL-4、IL-6、IL-10参与了老年脑卒中后肢体瘫痪患者骨质疏松症发病过程。
机构地区 河北保定解放军
出处 《脑与神经疾病杂志》 2005年第5期379-380,共2页 Journal of Brain and Nervous Diseases
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