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血清降钙素原测定对感染性疾病的观察 被引量:1

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摘要 目的探讨感染性疾病患者血清降钙素(PCT)原指标变化。方法运用B.R.A.H.M.SPCT-Q免疫胶体金半定量快速实验方法,检测310例感染性患者及50例健康者血清PCT水平。结果PCT水平按<0.5ng/ml、0.5~2.0ng/ml、2.0~10.0ng/ml和>10ng/ml4个等级。设PCT>0.5ng/ml为阳性值。在病毒感染性疾病组中,阳性为8.7%,其浓度以0.5~2.0ng/ml为主,细菌性感染组阳性为77.0%,其浓度以0.5~2.0ng/ml、2.0~10ng/ml为主,重度感染组(脓毒血症、MODS、全身炎性反应综合征等)阳性为97.6%,其浓度显著增高。与正常对照组及病毒感染组比较,细菌感染组及重度感染组血清PCT水平具有显著性差异(P<0.001)。结论病毒性感染疾病患者血清PCT水平不升高或轻度升高,而细菌性感染患者及重度感染患者血清PCT水平则明显升高,尤其以重度感染组患者为甚。
出处 《江西医学检验》 2005年第3期225-226,共2页 Jiangxi Journal of Medical Laboratory Sciences
关键词 降钙素原 感染
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  • 1Assicot M,GendrelH, et al.High sernm procalcitonin conccentrations in patients and infection[J].Lancet, 1993,341:515~518.
  • 2CASADO F J,BLANCO Q A. Procalcitonin,a new marker for bacterial infection[J] AnEsp Pediar,200,54(1):69~73.
  • 3Van lessuwen HJ Voorbij,HAM.Procalxitonin xonxentrations in the diagnosis of acute inflammatory reactions[J],Ned Tijdschr Geneeskd,2002.146:55~59.
  • 4Lorrot M.Moulin F, Coste J.et al, Prlcalcitonin in pediatric emergencies,comparsion with creactivr protein,intedukin-6 andinterferon alphain the differentiation between bacterical and infection [J],Presse Med.2000,29:128~134.
  • 5Nelyn E S,Whang KT,White J C,Mortality is increasd by procalcitonin and decreased byan antiserum reactive to procalcitonin in experinental sepsis[J],Crit Care Med,1998,26:1001~1006.
  • 6汪明明,崔速南,张景遥,孙玉秋,史兆章,张娟.血清降钙素原测定在感染性疾病中的诊断意义[J].中国抗感染化疗杂志,2002,2(4):215-217. 被引量:41

二级参考文献8

  • 1彭道泉.诊断性试验研究及评价[A].见:赵水平,彭道泉主编.现代临床科研方法学 第1版[C].长沙:中南大学出版社,2001.35.
  • 2Guerin S. Evaluation of the detection of procalcitonin by an immno-chromatography test: Brahms PCT-Q[J]. Ann Biol Clin (Paris),2000,58:613-614
  • 3Maruna P, Nedelnikova K, Gurlich R. Physiology and genetics of Procalcitonin [J]. Physiol Res,2000,49:S57-S61
  • 4Casado Flores J,Blanco Quiros A. Procalcitonin,A new marker for bacterial infecton[J]. An Esp Pediatr,2001,54:69-73
  • 5Korppi M, Remes S. Serum procalcitonin in pneumococcal pneumonia in children [J]. Eur Respir J, 2001,17:623-627
  • 6Martinot M, Hansmann Y, De Martino S, et al. Procalcitonin in pyelonephriti sand acute community-acquired pneumonia in adults[J]. Presse Med ,2001,30: 1091-1096
  • 7Herget-Rosenthal S, Marggraf G, Pietruck F, et al. Procalcitonin for accurate detection of infection in haemodialysis[J]. Nephrol Dial Transplant, 2001,16:975-979
  • 8Spahr L, Morard I, Hadengue A, et al. Procalcitonin is not an accurate marker of spontaneous bacterial peritonitis in patients with cirrhosis[J]. Hepatogastroenterology,2001,48:502-505

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  • 1Van den Bruel A, Haj-Hassan T, Thompson M,et al. Diagnostic value of clinical features at presentation to identify serious infec- tion in children in developed countries: A systematic review[J]. Lancet, 2010,375:834-845.
  • 2Christ-Crain M ,Jaccard-Stolz D,Bingisser R. Effect of procalci- tonin-guided treatment on antibiotic use and outcome in lower res- piratory tract infections: cluster-randomised,single-blinded inter- vention triM[J]. Lancet,2004,363 (9409):600-607.
  • 3Karzai W,Oberhoffer M ,Meier-HeUmann A, et al. Procalcitonin-a new indicater of the systemic response to severe infections [J]. In- fection, 1997,25(6):329-324.
  • 4Beckcr KL, Snider R, Nylen ES. Procalcitonin in sepsis and sys- temic inflammation: a harmful biomarker and a therapeutic target [J]. Br J Pharmacol, 2010, 159(3):253-264.
  • 5Schuetz P, Albrich W, Christ-Crain M, et al. Procaleitonin for guidance of antibiotic therapy [J]. Expert Rev Anti Infect Ther 2010, 8(5):575-587.
  • 6汪明明,崔速南,张景遥,孙玉秋,史兆章,张娟.血清降钙素原测定在感染性疾病中的诊断意义[J].中国抗感染化疗杂志,2002,2(4):215-217. 被引量:41

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