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卡维地洛对轻中度高血压患者血压变异性的影响

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摘要 目的探讨卡维地洛对轻、中度高血压的治疗效果及其对血压变异性(ABPV)的影响.方法计数法将轻、中度原发性高血压患者分成二组,分别用卡维地洛10 mg,2次/d;倍他乐克12.5~25 mg,2次/d.观察治疗前及治疗8周后肱动脉血压、动态血压等变化.结果治疗8周后,两组患者的平均收缩压(SBP)、舒张压(DBP)均有明显下降,差异显著(P<0.05).两组总有效率分别达到85.0%、82.5%;组间比较差异无显著性(P>0.05).卡维地洛组ABPV指标中24h SBP标准差及白昼SBP标准差分别下降4.6±1.8和4.4±1.6,与治疗前相比差异显著(P<0.05).DBP标准差和夜间ABPV指标也略见减低,但无显著性意义.倍他乐克组ABPV指标也见减低,但均无显著性差异.结论卡维地洛能显著降低轻、中度高血压患者的血压水平,同时能使部分ABPV指标降低.
出处 《实用药物与临床》 CAS 2005年第5期20-21,共2页 Practical Pharmacy and Clinical Remedies
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