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门控心肌灌注断层显像在临床的应用价值

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摘要 目的:评估门控心肌灌注断层显像(Gated-SPECT)在临床的应用价值。方法:对照70例临床怀疑或已知冠心病患者和12例正常对照者进行潘生丁药物负荷后和静息时门控心肌灌注断层显像。应用AutoQU ANT全自动定量软件获得心肌舒张末(ED)和收缩末(ES)心肌断层像,左室射血分数(LVEF)、舒张末期容积(ED V)、收缩末期容积(ESV)、局部室壁运动(W M)和局部室壁增厚率(W T)等定量指标。结果:(1)12例正常对照者负荷后LVEF、EDV、ESV值和静息时比较无明显改变。左室局部功能随室壁部位有较大差异。(2)门控和非门控心肌灌注断层显像比较:82例按非门控心肌灌注断层显像读片,29例(41%)未能明确诊断;结合门控心肌灌注断层显像读片,未能明确诊断数量减少至3例(4%)。(3)15例可逆性心肌灌注缺损中,5例严重心肌缺血患者表现负荷后LVEF值较静息时明显减低,ESV扩大;5例陈旧心肌梗死患者,平均LVEF、ESV和EDV值分别为30.60%、169m l、220m l。结论:门控心肌灌注断层显像可改善核素心肌灌注显像对冠心病的诊断灵敏度和特异性,值得临床推广应用。
作者 马步成 颜珏 李环 甄力莳
机构地区 中日友好医院核医学科
出处 《中日友好医院学报》 2005年第5期299-301,共3页 Journal of China-Japan Friendship Hospital
关键词 门控心肌灌注断层显像 ^99锝^m-甲氧基异丁基异腈
分类号 R817.4 [医药卫生—影像医学与核医学]
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参考文献8

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二级参考文献31

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中日友好医院学报
2005年 第5期

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