摘要
目的探讨定量感觉检查中振动觉阈值(VPT)测定和SemmesWeinstein单丝检测(SWME)对糖尿病的临床应用价值。方法采用生物感觉定量测试仪、128Hz分度音叉及SemmesWeinstein单丝检测167例正常人和172例2型糖尿病患者的VPT和触觉阈值,建立不同年龄正常人的VPT和触觉阈值参考值,并与糖尿病患者进行对比、分析。结果正常对照组(对照组)和糖尿病组(DM组)的VPT均与年龄相关,生物感觉定量测试仪所测的VPT1比较,DM组显著高于对照组,音叉测定的VPT2比较,DM组显著低于对照组;SWME结果在对照组中与年龄无相关性,而在DM组中则与年龄显著相关。两种方法测得的VPT均与SWME显著相关,使用生物感觉定量测试仪对于糖尿病多发性周围神经病变及有发生糖尿病足潜在危险的患者的检出率最高。结论SWME和VPT测定结合临床症状,能更方便、可靠地诊断糖尿病多发性周围神经病变。
Objective To investigate the clinical value of vibration perception thresholds （VPT） examination and Semmes-Weinstein monofilament examination （SWME） in diabetic peripheral poly-neuropathy （DPN） screening. Methods The VPT and SWME were administered with 167 healthy control subjects and 172 type 2 diabetic patients with biothesiometer, 128 Hz graduated tuning fork and Semmes-Weinstein monofilaments. Results We established normality data of VPT. VPT values were significantly correlated with ages in DM and non-DM subjects. Mean VPTl values measured by biothesiometer were significantly higher in DM subjects than in healthy control subjects, while mean VPT= values measured by tuning fork were significantly lower in DM subjects than in healthy control subjects. SWME values had no correlation with age in healthy control subjects, while had significant correlations with age in DM subjects. Those two kinds of VPT values were both significantly correlated with SWME values. Using biothesiometer could detect more patients with DPN and those at risk for diabetic foot complications than using tuning fork or Semmes-Weinstein monofilaments. Conclusion The combined use of VPT detection, SWME and other clinical features is useful and convenient for DPN screening.
出处
《中华物理医学与康复杂志》
CAS
CSCD
北大核心
2005年第10期610-613,共4页
Chinese Journal of Physical Medicine and Rehabilitation
