摘要
目的验证安乐片与劳拉西泮治疗广泛性焦虑症的临床疗效及副反应。方法采用随机分组的方法,将符合CCMD-3诊断标准的60例广泛性焦虑症分为安乐片组(30例)、劳拉西泮(30 例),疗程4周,用焦虑自评量表(SAS),Hamilton焦虑量表(HAMA)和副反应量表(TESS)评定疗效和副反应。结果安乐片与劳拉西泮疗效相当(P>0.05)。治疗第4周两组SAS、HAMA及HAMA因子分的减分比较有非常显著性差异(P<0.01),两者副反应相当,均较轻微,不影响治疗效果。结论琦云安乐片治疗广泛性焦虑症有效,副反应轻微。
Objective To study the clinical effects and side effects of Anle plan and lorazepam in the treatment of generalized anxiety disorder. Methods 60 patients who met the criteria of CCMD-3 for generalize anxiety,were treated with Anle pian (30 patients) and Lorazepam (30 patients) treatment for 4 weeks. The clinical effects and side effect were tested with HAMD,SAS and TESS. Results Anle plan was similar to Lorazepam in clinical effect and side effects (P 〉 0. 05). After 4 weeks treatment, the scores of SAS, HAMA and factors of HAMA of two groups were significantly differences (P 〈 0.01). Anle plan and Lorazepam have light side effects. Conclusions Anle pian is an effective and safe antianxieric.
出处
《神经疾病与精神卫生》
2005年第3期176-177,共2页
Journal of Neuroscience and Mental Health
关键词
安乐片
劳拉西泮
广泛性焦虑症
Anle plan
Lorazepam
Generalized anxiety disorder