摘要
目的探讨抗精神病药合并盐酸丁咯地尔对以阴性症状为主[1]的精神分裂症认知功能的影响。方法将以阴性症状为主的精神分裂症患者共46例随机分为实验组与对照组,并分别使用抗精神病药和抗精神病药合并盐酸丁咯地尔治疗4周,采用韦氏智力量表和韦氏记忆量表来评定治疗前后患者认知功能的改变。结果实验组和对照组在治疗后比治疗前言语量表、操作量表、全量表和记忆量表分有明显提高,且实验组较对照组在言语量表、操作量表、全量表和记忆量表分上也有明显改善。结论合并盐酸丁咯地尔有助于提高以阴性症状为主的精神分裂症患者的认知功能。
Objective To study effect of antipsychotic with buflomedil hydrochlorde in the treatment of negative schizophrenia on cognition function. Methods 46 schizophrenic patients with negative symptoms were randomly divided into the experiment group and the control group, and treated with antipsychotic or antipsychotic with buflomedil hydrochlorde for 4 weeks. All patients were assessed in pretreatment and post-treatment by Wechsler adult intelligence scale （WAIS） and Wechsler memory scale （WMS）. Results After treatment, the language scale, operation scale ,total scale, and memory scale were improved significantly in both the case groupand experiment group. Also, compared to the control group ,the language scale, operation scale,total scale, and memory scale were improved obviously in the Experiment Group. Conclusion Uniting antipsychotic and buflomedil hydrochlorde help to improve the cognition function in negative schizophrenia.
出处
《中国健康心理学杂志》
2005年第5期326-328,共3页
China Journal of Health Psychology
