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牵引成骨术分子生物学机制研究进展 被引量：1

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摘要 目前的研究表明缓慢的牵张刺激可增强骨痂中各种生长因子(TGF-βs、BMPs、IGF-1、FGF-2、VEGF)表达和细胞外基质(胶原蛋白Ⅰ、骨钙素、骨桥接素和骨连接素等)的生成。本文就牵引成骨术分子生物学机制近年来的研究进展作一综述。
作者 易红良 殷善开
机构地区 上海交通大学附属第六人民医院耳鼻咽喉科鼾症诊治中心
出处 《国外医学（耳鼻咽喉科学分册）》 2005年第5期302-304,共3页 Foreign Medical Sciences(Section of Otolray Ngology Foreign Medical)
关键词 骨生成 内脱位(Osteogenesis Distraction) 生长物质(Growth Substances) 细胞外基质(Extracellular Matrix) 分子生物学机制 牵引成骨术 机制研究
分类号 R346 [医药卫生—基础医学]
  • 相关文献

参考文献19

  • 1唐杰,胡静,王志国,高占巍,李继华.兔下颌牵张后血管内皮生长因子在新骨组织中的定位表达[J].上海口腔医学,2003,12(3):191-193. 被引量：7
  • 2Rowe NM, Mehrara BJ, Dudziak ME, et al. Rat mandibular distraction osteogenesis: Part 1. Histologic and radiographic analysis. Plast Reconstr Surg, 1998 , 102 (6) : 2022-2032.
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二级参考文献11

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共引文献6

同被引文献36

  • 1Snyder CC,Levine GA,Swanson HM,et al. Mandibular lengthening by gradual distraction: Preliminary report [J] .Plast Reeonstr Surg, 1973,51 (5):506-508.
  • 2McCarthy JG. The role of distraction osteogenesis in the reconstruction of the mandible in unilateral craniofacial microsomia[J]. Clin Plast Surg,1994,21(4):625-631.
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  • 4Rachmiel A , Levy M, Laufer D,et al. Multiple segmental gradual distraction of facialskeleton: an experimental study [J]. Ann Plast Surg, 1996,36(1):52-59.
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  • 7Polley JW, Figueroa AA. Management of severe maxillary deftciency in childhood and adolescence through distraction osteogenesis with an external, adjustable, rigid distraction device[J].J Craaiofac Surg,1997,8(3): 181-185.
  • 8Henkel KO, Ma L, Lenz JH, et al. Closure of vertical alveolar bone defects with guided horizontal distraction osteogenesis: an experimental study in pigs and first clinicalresults [J] .J Craniomaxillofac Surg, 2001,29(5):249-253.
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引证文献1

国外医学（耳鼻咽喉科学分册）
2005年 第5期

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