摘要
目的观察病窦停(Bingdouting,BDT)胶囊对病态窦房结综合征(病窦综合征)的治疗作用。方法用20%甲醛液外敷窦房结区制备病态窦房结综合征模型,观察BDT胶囊对家兔病窦模型的心率及窦房结电生理指标的影响。结果BDT胶囊可以提高窦性心率,明显缩短窦房结传导时间(SACT)及校正窦房结恢复时间(CSNRT)。结论BDT胶囊对家兔病窦综合征具有明显治疗作用。
Objective To observe the effect of Bingdouting capsule （BC） on rabbit model of sick sinus syndrome. Methods Rabbit models of sick sinus syndrome were established by external application of 20 % methanal on the region of sinoatrial node. The effect of BC on heart rate and electrophysicological parameters of sinoatrial node was observed. Results BC markedly increased the heart rate, shortened the sinoatrial conduction time （SACT） and corrected sinoatrial node recovery time （CSNRT） . Conclusion BC has an obvious effect for the treatment of sick sinus syndrome in rabbits.
出处
《中药新药与临床药理》
CAS
CSCD
2005年第5期327-329,共3页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
病窦停胶囊
病窦模型
心率
窦房结传导时间
校正窦房结恢复时间
Bingdouting capsule
Sick sinus syndrome model
Heart rate
Sinoatrial conduction time
Sinus node recovery time
