摘要
应用电导方法研究了生姜成分从纤维素/聚乙二醇/生姜共混纤维中的缓释。研究结果表明:随着释放环境温度的升高,药物的释放愈加明显;但是当环境温度接近纤维本体玻璃化转变温度时,药物释放会受到抑制。生姜成分从药物纤维中的释放遵循零级、一级和二级并存的较复杂的动力学模型,但其中起主导作用的是零级释放速率常数。
Taking conductivity as a tool to study the ginger components released from a cellulose/ poly（ethylene glycol）/ginger blend fiber, results showed that this process was controlled by the temperature and in general the higher the temperature the faster is the release, except the temperature approaches to a phase change temperature for bulk fiber. A model deduced based on recorded conductivity curves indicated that the drug release was following a complex model because the rate constants determined to have note only in zero and first, but also in second. However, the truth is of them the zero rate constant to be a dominator due to it higher than others.
出处
《纤维素科学与技术》
CAS
CSCD
2005年第3期25-28,共4页
Journal of Cellulose Science and Technology
基金
教育部留学人员启动基金资助项目(2B10601)
关键词
生姜
共混纤维
缓释
电导
动力学模型
ginger
blend fiber
drug release
conductance
dynamical model
