摘要
目的观察地塞米松复合芬太尼用于鼻内镜术(ESS)后静脉持续镇痛效果。方法ESS40例,随机分为两组,F组20例,芬太尼1.0mg,生理盐水稀释至100ml(芬太尼10μg/ml)用于术后镇痛;FD组20例,术毕静脉注射地塞米松0.07mg/kg后,芬太尼1.0mg+地塞米松10mg,生理盐水稀释至100ml(芬太尼10μg/ml,地塞米松100μg/ml)用于术后镇痛。使用一次性静脉持续镇痛泵,注射速度为2ml/h,分别于术后4、8、12、24、36、48h随诊记录VAS值等指标。结果术后VAS评分,FD组分别为2.53、2.57、2.60、2.58、2.64、2.58,F组为2.77、3.17、2.93、3.03、3.09、3.01。结论ESS术后于芬太尼静脉持续镇痛基础上加用地塞米松可明显改善术后镇痛效果。
Objectives To evaluate the intravenous analgesic effect of dexamethasone combined with fentanyl after ESS. Methods 40 patients undergoing ESS under combined general anesthesia with deliberated hypotention were randomly allocated into two groups. Pain management was initiated postoperatively with 1.0mg fentanyl in group F and 1.0mg fentanyl＋10mg dexamethasone followed the injection of 0.07mg/kg dexamethasone in group FD, which were dissolved into 100ml 0.9% sodium saline respectively （F： fentanyl 10μg/ml, FD;fentanyl 10μg/ml＋dexamethasone 100μg/ml）. Disposable continuous analgesic pump was employed for each patient with injection rate of 2ml/h. Results There was significant difference of mean VAS value between the two groups during the 48 hours postoperatively （P〈0.01）. Conclusions Dexamethasone improves analgesic effect when combined with fentanyl intravenously in the postoperative pain management for ESS patients.
出处
《北京医学》
CAS
2005年第9期540-542,共3页
Beijing Medical Journal
