摘要
报告39例小肝癌临床治疗结果,其中预防性动脉内化疗栓塞17例,对照组22例,旨在减少肝内复发、转移和进一步提高生存率。预防治疗组共行50次治疗,平均2.95±0.85次/人,最多7次。治疗组所有患者首次血管造影均未见明显的病灶。治疗组中,8例根治术后1月内持续 AFP>20μg/ml,进行预防肝动脉内化疗栓塞(碘化油3～5ml)。治疗组1,3,5年生存率为100%,91.5%,84.75%,对照组22例患者,在未检出病灶前均未行任何常规及动脉内化疗或栓塞。对照组为91.7%,63.5%,40.91%,两组生存率比较P<0.01。本研究显示预防性介入放射学处置可进一步提高小肝癌根治术后的生存率。
PURPOSE:For minimizing recurrence and metastasis of hepatocellular carcinoma (HCC),and evaluating preventive hepatic arterial chemoinfusion (P-HAI) or combination with chemoembolilzation (P-HAE) as an alternative therapy following the focus radical resection in small HCC patients.METERIALS AND METHODS:17 patients with HCC in early stage received preventive interventional treatment within three weeks to three months after focus radical resection.Meanwhile 22 similar patients as a control group were untreated with P-HAI or P-HAE.RESULTS:In the preventive international therapy group,50 times of treatment were performed with a mean of three times per patient,and an utmost of seven times.P-HAE was undergone lipoidal 3～5ml in eight patients with AFP abnormality (>20μg/L) after surgery in one month.The survival rate for 1,3,5yr were 100%(n=17),91.5%(n=16) and 84.7% (n=14) respectively in the therapy group,and in the control group 95.45% (n=21),72.7% (n=16),40.91%(n=9) respectively.Sur- vival rate between two groups showed significant difference (P<0.01).CONCLUSION: Surgical resection combined with P-HAI or P-HAE may minimize liver cancer recurrence and metastasis and increase patient's survival rate.
出处
《介入放射学杂志》
CSCD
1996年第1期12-14,共3页
Journal of Interventional Radiology
关键词
肝癌
治疗
药物疗法
栓塞疗法
Hepatic neoplasm
Interventional therapy
Therapeutic chemoembolization
Preventive
Survival rate
