摘要
铁(Ⅲ)核苷酸配位化合物与转铁蛋白的相互作用王继波,赵辉,孙衍增(青岛医学院化学教研室青岛266012)关键词转铁蛋白,核苷酸,动力学转铁蛋白广泛存在于人体细胞及体液中[1~5],有许多关于铁在小分子配体与转铁蛋白之间交换的研究[6,7],但铁(Ⅲ)...
We have studied the kinetics of interaction between ferric nucleotide coordination compounds and transferrin with spectrophotometry. Results showed that the exchange rate of ferric ion is Fe(Ⅲ)PYR>Fe(Ⅲ)ATP>Fe(Ⅲ)ADP>Fe(Ⅲ)AMP.The exchange reactions between Fe(Ⅲ)ATP,Fe(Ⅲ)ADP or Fe(Ⅲ)PYR and deferrization transferrin are second order reactions, but the reaction mechanism of Fe(Ⅲ) ATP and Fe(Ⅲ) PYR is different from that of Fe(Ⅲ)ADP.The exchange reaction of Fe(Ⅲ) AMP is a first order reaction.
出处
《应用化学》
CAS
CSCD
北大核心
1996年第1期109-111,共3页
Chinese Journal of Applied Chemistry