摘要
目的探讨15例变应性肉芽肿性血管炎(CSS)患者的临床表现及病理特点,提高对该病的认识。方法回顾性分析总结15例CSS患者的临床表现及实验室资料。结果15例中有7例分别以多发性单神经炎(3/7)、胃肠道病变(2/7)及皮肤病变(2/7)为首发症状。全部病例周围血嗜酸细胞增高,活检显示CSS的3种典型的病理改变通常出现在疾病的不同阶段。结论CSS单次活检可能看不到病变全貌,必要时需进行多次活检。
Objective In order to enhance the understanding of Churg-Strauss syndrome, the clinical manifestations and the pathological features of 15 patients were reviewed. Methods The clinical and pathological findings of 15 patients with Churg-Strauss syndrome admitted to Peking Union Medical College Hospital were retrospectively analysed. Results In 15 cases, the initial clinical manifestations were poly-mononeuropathy, gastrointestinal disorders and skin lesions. Peripheral eosinophilia was significant in all cases. Biopsies were taken in all cases. The typical pathological features usually demonstrated in diffiferent stage of the disease. Conclusions If a patient shows a clinical manifestation of fever, skin lesions, neuropathy, abdominal pain and diarrhea, as well as eosinophilia in peripheral blood, the diagnosis of Churg-Strauss syndrome should be considered. It is necessary to take biopsies from several sites at different time.
出处
《中华风湿病学杂志》
CAS
CSCD
2005年第9期552-553,i0001,共3页
Chinese Journal of Rheumatology
