摘要
目的:研制双黄连颗粒剂并进行质量考察。方法:选用明胶、甘露醇和甜菊苷等作为矫味剂制备双黄连颗粒剂,并考察其防潮性能。结果:当药物∶明胶∶甘露醇配比为1∶2∶1.5时,双黄连味甜,绝大部分颗粒疏松;放置30d时吸潮率为5.51%。结论:本双黄连颗粒剂制备工艺简单、口味甜、防潮性能优越,与已报道文献相比辅料用量少且崩解快,值得开发和推广。
Objective： To research and prepare Shuanghuanglian granules. Methods： To choose gelatin and mannitol as corrective agents for preparing Shuanghuanglian granules and to investigate its humidity resistance. Results： When the proportion of Shuanghuanglian, gelatin and mannitol is 1 ： 2 ： 1.5, Shuanghuanglian granules have the bitter taste, water absorption is 5.51% in one month. Conclusion： Shuanghuanglian granules have good taste and good humidity resistance. Their preparation process is simple and the content of excipient is low.
出处
《中国药业》
CAS
2005年第9期63-64,共2页
China Pharmaceuticals
关键词
双黄连
颗粒剂
制备
质量考察
Shuanghuanglian
granules
preparation quality investigation
