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利维爱治疗绝经相关疾病的研究进展 被引量:1

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摘要 利维爱是人工合成的甾体激素,口服后在体内代谢为具有雌、孕、雄3种激素样的物质,这些代谢产物在外周血中以不具有生物活性的硫酸盐形式存在,经血流至骨骼、大脑及泌尿生殖道等部位时,在组织中硫酸酯酶的作用下,脱去硫酸后发挥雌激素样作用。其作用机制及临床效应,与传统的激素替代治疗(HRT)有明显的不同。就其在防治绝经相关疾病方面的最新研究进展做如下综述。
作者 陈静 刘晓瑷
出处 《国外医学(计划生育分册)》 2005年第5期236-239,共4页
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