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经阴道补充雌激素的临床研究进展 被引量:14

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摘要 阴道补充雌激素是绝经后激素替代治疗(HRT)的一种给药途径,可避免胃肠道吸收和肝脏首过效应,低剂量有效,副反应发生率低,其中阴道环是接受性最好的一种剂型。阴道补充低剂量雌激素对萎缩性阴道炎有肯定疗效,对尿失禁和反复尿路感染可能有效。当一定剂量连续使用时,也可产生泌尿生殖道以外的效应,如缓解潮热,影响血脂代谢和骨代谢等。对子宫内膜刺激小,但长期使用对子宫内膜也可能有潜在危险。
作者 周蒨 刘晓瑷
出处 《国外医学(计划生育分册)》 2005年第5期225-228,共4页
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