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绝经后2型糖尿病患者尿路感染的雌激素治疗 被引量:4

Estrogen therapy for urinary tract infection of type 2 diabetes mellitus in postmenopausal women
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摘要 目的 研究雌激素治疗绝经后2型糖尿病患者尿路感染的疗效.方法 将83例绝经后2型糖尿病尿路感染患者随机分为两组,对照组(42例)根据药敏给予抗生素治疗配合胰岛素控制血糖,治疗组(41例)在对照组的基础上加用雌二醇凝胶.观察两组的临床疗效及细菌学疗效.结果 治疗组痊愈31例,有效7例,无效3例;对照组痊愈15例,有效14例,无效13例.两组临床疗效比较差异有统计学意义(P<0.05),两组治疗后细菌学疗效比较差异亦有统计学意义(P<0.05).结论 在抗生素治疗的基础上加用雌二醇,对绝经后2型糖尿病合并尿路感染患者疗效显著. Objective To investigate the curative effect of estrogen therapy on urinary tract infection of type 2 diabetes mellitus in postmenopausal women. Methods Eithty-three postmenopausal women who had urinary tract infection of type 2 diabetes mellitus were enrolled and were randomly divided to receive antibiotic therapy(levofloxacin was used before obtaining of drug susceptibility results) alone (control group) or in combination with estradiol gel (treatment group). The clinical efficacy and bacteriological therapeutic effect in the two groups were evaluated. Results The treatment group was better than control group in both clinical efficacy and bacteriaological therapeutic effect. Conclusions Antibiotic therapy in combination with estradiol gel showed remarkable efficacy for patients with type 2 diabetes mellitus associated with urinary tract infection in postmenopusal women.
出处 《中国实用医刊》 2010年第13期21-22,共2页 Chinese Journal of Practical Medicine
关键词 2型糖尿病 尿路感染 雌激素 绝经后 Type 2 diabetes mellitus Urinary tract infection Estrogen Postmenopausal
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