摘要
目的观察支气管哮喘患儿血清尿酸(UA)水平的变化,探讨其临床意义。方法采用美国Beckman公司SynchronCX5△全自动生化分析仪,检测30例(轻中度18例,危重度12例)支气管哮喘患儿急性期及其中22例处于恢复期的患儿血清UA水平,并以20例正常小儿作为对照。结果支气管哮喘患儿急性期血清UA水平升高,与恢复期及正常对照组比较,差异均有显著意义(P<0·01),恢复期血清UA水平下降,与正常对照组比较差异无显著意义(P>0·05);血清UA水平的高低与病情严重程度相关,危重度组高于轻中度组,差异有显著意义(P<0·01)。结论支气管哮喘患儿UA水平与病情相关,检测血清UA水平,能为临床判断病情、评估预后及指导治疗提供一个有价值的生化指标。
Objective To observe serum uric acid（UA） level change for the children suffered from bronchial asthma and explore its clinical significance. Methods Used Synchron CX5△ full auto-biochemical analyzer made by Beckman company,America. The serum UA concentration was tested in 30 cases（light-medium degree of 18 cases and serious degree of 12 cases） of children suffered from acute period of bronchial asthma,of which,22 cases of children suffered from bronchial asthma compared for recovery period with 20 cases of normal children for comparison. Results The children suffered from acute period of bronchial asthma with higher serum UA compared with recovery period and normal children for complarson, the differences were all significant（ P 〈 0.01） ;Serum UA level down for recovery period compared with normal children for comparison, the difference was not significant（ P 〉 0.05 ） ; The higher serum UA level had relation with serious disease situation,the serious patients group was higher than lightmedium group with very significant situation（P 〈0.01 ）. Conclusions The serum uric acid（UA） level for the children suffered from bronchial asthma has relation with disease situation,tested serum uric acid（UA） level for diagnosis of disease situation, evaluation for prognosis and instruction for treatment so as to provide one valuable biological index.
出处
《中国基层医药》
CAS
2005年第8期986-987,共2页
Chinese Journal of Primary Medicine and Pharmacy
