摘要
目的:探讨血清白细胞介素-18水平(IL-18)与不同类型冠心病患者及其他心血管病危险因素的关系。方法:分别测定各研究组的血清IL-18水平,比较各组间的差异及与其他心血管病危险因素的关系。结果:冠心病患者血清IL-18水平明显高于对照组,其中急性心梗和不稳定心绞痛组IL-18与稳定型心绞痛组及对照组比较有差异性(P<0.05)。IL-18冠心病的并发症之间存在一定的相关性。结论:IL-18水平是反映冠脉粥样病变的炎症反应的主要指标之一,也是预示急性冠脉事件发生的标志。
Objective： To investigate the relationship between interleukin- 18 （IL- 18） and coronary heart disease and other cardiovascular risk factors. Methods：The level of serum IL - 18 in groups were measured and compared. The relationship between IL- 18 and other cardiovascular risk factors was analyzed. Results： Compared with control group, the level of IL - 18 in patients with coronary heart disease was higher, specially in acute myocardial infarction group and unstable angina group. The difference was significant （P〈 0.05）. IL- 18 was related to complications of coronary heart disease. Conclusion ：The level of IL- 18 is one of major indictors inflecting inflammation in coronary atherosclerotic lesion. It also predict the occurance of acute coronary events.
出处
《内蒙古医学杂志》
2005年第9期778-781,共4页
Inner Mongolia Medical Journal
关键词
白细胞介素-18
冠心病
Interleukin - 18（ IL - 18）
Coronary heart disease
