摘要
目的研究复方免疫散多糖及其拆方的体外抗氧化作用。方法测定3种多糖对·OH、DPPH·、超氧阴离子自由基的清除能力,用硫代巴比妥酸法测定其对脂质过氧化的抑制作用以及金属离子的螯合,评价复方免疫散多糖及其拆方的抗氧化活性。结果复方免疫散多糖及其拆方呈剂量依赖性地清除·OH、DPPH、超氧阴离子自由基,抑制脂质过氧化及螯合金属离子。结论复方免疫散多糖及其拆方在体外具有抗氧化能力。
OBJECTIVE To study the antioxidant capability( in vitro) of polysaccharides extracted from Complex prescription immunization powder and different combinations of ingredients of a formula. METHODS The anti-oxidative capacity of three kinds of polysaccharides on 1,1-diphenyl-2-picrylhydrazyl radical( DPPH) ,hydroxy radical and superoxide anion were assayed. Meanwhile, the inhibiting effects on lipid peroxidation were studied by triobarbituric acid( TBA) system and metalion chelate reacting system in vitro. RE...
出处
《华西药学杂志》
CAS
CSCD
北大核心
2010年第5期539-541,共3页
West China Journal of Pharmaceutical Sciences
基金
石河子大学高层次人才科研启动资金专项(RCZX200758)
石河子大学自然科学与技术创新重点项目(ZRKX2009ZD01-2)
关键词
复方免疫散
拆方
多糖
抗氧化
Complex prescription immunization powder
Different combinations of ingredients of a formula
Polysaccharide
Antioxidation
