摘要
[目的]通过观察电针"石门"穴对下丘脑GnRH的影响,探讨电针小鼠"石门"穴有影响下丘脑-垂体-卵巢轴的作用。[方法]清洁级昆明雌、雄性小鼠各30只,阴道检查发现阴栓为妊娠第1天。按体重随机分为空白组、电针组、西药组,每组10只。电针组:妊娠第1～5天早9时电针;西药组:妊娠第4天早9时皮下注射米非司酮;空白组:在相同时间抓取固定,但不予针刺;取下丘脑,用放射免疫法测定GnRH的水平。[结果]电针组GnRH比空白组低,与米非司酮组的激素水平接近。[结论]电针"石门"穴能对下丘脑GnRH产生影响,进而说明电针"石门"穴能够影响下丘脑-垂体-卵巢轴。
[Objective]By observing the electro-acupuncture 'Shihmen' points to the impact of hypothalamic GnRH to explore electro-acupuncture ' Shihmen' Point in mice affecting the hypothalamus-pituitary -ovarian axis function.[Method]Clean Kurming female,male mice,each 30.Vaginal suppository for vaginal exam-ination revealed that the first day of pregnancy.According to body weight were randomly divided into blank group,electro-acupuncture group,western medicine group,10 in each group.Electro-acupuncture group:Pregnancy 1-5 days earlier at 9:00 electro-acupuncture;western medicine group:9:00 the 4th day of pregnancy the first subcutaneous injection of mifepristone;blank Group:crawling in the same fixed time,but not acupuncturing,measuring by radioimmunoassay the level of GnRH.[Results]Electro-acupuncture group than the blank group GnRH,with the mifepristone group close to the hormone levels.[Conclusion] Electro-acupuncturing 'Shihmen' hole can have an impact on the hypothalamic GnRH,and electroacu -puncturing 'Shihmen' hole can affect the hypothalamus-pituitary-ovarian axis.
出处
《实用中医内科杂志》
2009年第11期28-29,共2页
Journal of Practical Traditional Chinese Internal Medicine
