摘要
应用免疫组织化学方法,结合超微结构观察,分析了19例垂体泌乳素腺瘤的形态和机能。发现泌乳腺素瘤体积与血清泌乳素浓度密切相关。泌乳素阳性细胞百分率与术前血清泌乳素浓度无关,可能与瘤细胞分泌方式及自身分泌状况的影响有关。由此认为不能仅通过阳性细胞百分率反映血清泌乳素水平。此外尚发现稀疏颗粒型腺瘤属于高分泌功能腺瘤,而密集颗粒型腺瘤则处于低分泌功能状态。
Electronmicroscopical study,radioimmunoassay and immunohistochemical semiquantitative estimation, of 19 cases of prolactin secreting pituitary adenomas are presented. As comparing and correlating the preoperative serum prolactin levels,the percentage of prolactin positive-staining cells and the size of tumors,we found some factors which might affect the serum prolactin levels,1)Serum prolactin levels is positively correlated with tumor size;2) The secreting way of tumor cells may be related to serum prolactin levels; 3) Serum prolactin levels are restained by the secreting condition of cells themselves, so that serum levels can not be reflected quantitatively by the percentage of prolactin positive-staining cells alone.
出处
《中华神经外科杂志》
CSCD
北大核心
1989年第1期32-35,共4页
Chinese Journal of Neurosurgery
