摘要
本实验将大鼠的两侧颈动脉结扎，以大鼠暗环境被动回避试验作为学习记忆指标，发现该大鼠模型出现了持续性的学习记忆障碍，作组织切片发现８０％模型出现脑梗塞灶。本研究提示该脑梗塞模式可作为学习记忆行为检查的依据。
The purpose of this study is to examine histological and behavioral changes following the bilateral carotid arteries ligation in rats.For behavioral study,step-through type dark avoidance task were performed 1,2,3 weeks after the ischemia.These results showed persistent impairment of learming and memory in ischemic rats.The incidence of ischemic lesion was 80% in histological examination This may be a useful model for the study of behavioral changes on cerebral ischemia.
出处
《中国行为医学科学》
CSCD
1995年第1期21-22,共2页
Chinese Journal of Behavioral Medical Science
关键词
脑梗塞
学习
记忆
脑血管疾病
Cerebral Ischemia Rats Learning and Memory
