摘要
本实验利用左大脑中动脉梗塞的大鼠模型，采用检查脑组织钙、脑梗塞体积、脑含水量及水迷路试验。观察了尼莫地平（ＮＤ）对局灶性脑梗塞的保护作用，结果表明ＮＤ减轻了神经细胞钙超载和脑水肿，缩小了梗塞范围，明显改善了学习和记忆。
Using rat middle cerebral artery occlusion (MCAO) model, the calcium、water contents and the volume of cerebral infarction were measured,the water-maze test was also determined. We have observed that nimodipine had protective effect on the brain. We found that the nimodipine might lessen brain's calcium overload, brain edemaand the volume of cerebral infarction and significantly recover the function of learning and memory after MCAO.
出处
《中国行为医学科学》
CSCD
1995年第3期120-122,共3页
Chinese Journal of Behavioral Medical Science
关键词
尼莫地平
脑梗塞
学习
记忆
药理学
Nimodipine Cerebral infarction Learning and Memory Calcium Rat.
