摘要
为了解应激状态下机体的神经递质──内分泌─—免疫系统功能的变化规律，我们对一组冠心病住院患者的尿ＭＨＰＧ、血浆皮质醇及白细胞介素Ⅱ进行观察，结果发现冠心病亚型、病程、焦虑情绪及不同行为模式均影响其神经──内分泌──免疫反应。其中，尿ＭＨＰＧ与血浆皮质醇变化趋势一致，而ＩＬ－２则与皮质醇相反。对于这类心血管病患者，尿ＭＨＰＧ不如皮质醇及ＩＬ２敏感。
Urine
MHPG, plasma cortisol and interleukin-2 in 66 patients with coronary heart disease (CHD)were
observed and the behavioral pattern of patients were assessed. The results revealed a
inreased activities in HPA axis and declined immune function in patients after acute attack of
CHD,though many factors,such as the subtype of CHD,the course of disease ,the patients’
anxiety level and behavior pattern, might influence the respnse in neuro-endocrine-immune
system, The plasma cortisol and urine MHPG changed in the same direction,while interleukin
changed inoppossite direction. For these CHD patients ,plasma cortisol and interleukin-2
appeared to be more sensitive indicatorsof response in system of neuro-endocrine-immune
than urine MHPG.
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
1995年第2期57-59,共3页
Chinese Mental Health Journal
关键词
冠心病
尿MHPG
皮质醇
白细胞介素Ⅱ、A型行为模式
Coronary heart disease ,interleukin-2,urine MHPG,plasma
cortisol,type A behavior pattern
