摘要
本文报道从伞形科植物明党参根的水溶液中,分离得一种无色结晶(晶Ⅵ),经理化、色谱、光谱和x-衍射分析,确定晶Ⅵ为L-天门冬酰胺(L-Asparagine)。晶Ⅵ是从该植物中首次得到,药理实验证明其具有祛痰、止咳、平喘作用。用高效薄层扫描法测定其不同产地药材中的含量,结果表明,江苏句容产者含量最高,为1.07％。
From the water solution of the dried roots of Changium smyrnioides wolff (Umbelliferae) ,a colourless transparent crystal, named crystal Ⅵ was isolated. Its structure was identifed as L-As-paragine by means of physicochemical,chromatographic,spectral and x-ray diffraction analysis. Crystal Ⅵ was first obtained from this plant. Pharmacologic experiments proved that the crystal had expelling phlegm, arresting coughing and relieving asthma effects. Its contents in the roots of Changium smyrnioides wollf in different habitats were also determined by high-performance thinlayer chromatographic scanning. The results indicate that the content of L-Asparagine in the roots collected in Jurong county,Jiangsu province is the highest(l. 07%).
出处
《天然产物研究与开发》
CAS
CSCD
1995年第2期1-5,共5页
Natural Product Research and Development
基金
江苏省教委自然科学基金
关键词
明党参
分离
鉴定
中药化学
化学成分
Changium smyrnioides,L-Asparagine,x-ray diffraction analysis,High-performance thinlay-er,chromatographic scanning quantity,Pharmacology
