摘要
采用本室建立的生物素－抗生物素蛋白－酶联免疫吸附测定法（ＢＡ－ＥＬＩＳＡ），检测健康儿童组、慢性肝炎患儿组的血清转铁蛋白（Ｔｆ）含量，并与患儿肝穿刺标本病理变化作对比研究。结果显示，慢性肝炎组血清Ｔｆ含量明显低于健康儿童组；Ｔｆ含量的降低与肝细胞损害程度具有相关性，慢性活动性肝炎（ＣＡＨ）的血清Ｔｆ下降程度比慢性迁延性肝炎（ＣＰＨ）更为显著。
The relationship between the quantitative changes of serum transferrin(Tf) by BA-ELISA and the pathologic changes of hepatocytes by needle liver biopsy in 20 cases of chronic hepatitis in children was studied.The results indicated that 1)serum Tf of chronic hepatitis in children was 1.36±0.40/Land was significantly lower than that in normal healthy children 2)tne decrease of serum Tf was closely related to the hepatocellular injury which was more significant in chronic active hepatitis rhan that in chronic persistent hepatitis.It may be helpful to judge the injury level of hepatocyte in chronic hepatitis children for working out an ideal therapetic scheme.
出处
《上海医科大学学报》
CSCD
1995年第4期268-271,共4页
Journal of Fudan University(Medical Science)
