摘要
为分析影响妊娠合并ＳＬＥ妊娠结果的危险因素，根据多年临床经验，选择１４项可能影响ＳＬＥ孕妇妊娠结果的因素，通过分析提示：生产次数、血压、强的松用量、血沉、肝功能等因素对ＳＬＥ孕妇的妊娠结果有一定的影响。将病人受孕时疾病所处的状态分为缓解期、控制期、活动期和妊娠时初次发病４种状态，比较４种状态下受孕后对新生儿体重、分娩孕周的影响后得出：在疾病的活动期受孕，新生儿出生时体重及分娩孕周明显低于其它３组（Ｐ＜０．０５），提示ＳＬＥ患者应在疾病缓解期或控制期受孕较为安全。
Among the 14 selected factors to assess the possibility of interferece with the outcome of plegnacy complicated with SLE, increas of ESR,impairment of liver function,increas in parity, large dosage of prednisone and hypertension had definite adverse effect. According to the clinical status of SLE at the beginning of conception, these patients were divided into 4 groups:(1)remission;(2)controlled;(3)active;(4)and primary. The outcome of pregnancy of these 4 groups was compared. The weights and gestational. wddks of the neonates in the active group were significantly lower than those of the other 3 groups(0.0001<P<0.05).The best time of conception for SLE patients was at the remission or controlled stage, when the patiens were treated with prednisone in a dose of 5-15mg/d for more than 6 months or without any medication at least for one year, for it was safer, and the relapsing tate of SLE was less.
出处
《上海第二医科大学学报》
CSCD
1995年第1期5-9,共5页
Acta Universitatis Medicinalis Secondae Shanghai
关键词
妊娠并发症
系统性红斑狼疮
危险因素
systemic lupus erythematosus, outcome of pregnancy, risk factor conception
