摘要
对4所精神病院较近期入院、初次发病年龄在45岁以上的晚发性精神分裂症患者共228例进行观察,以同期住院的45岁以下、初次发病的精神分裂患者309例为对照。结果发现,晚发组文化程度较低,发病前有精神或躯体因素为诱因者较多见,以急性或亚急性起病较多,早期症状以神经症样症状较多见,而入格改变较少见,临床类型以偏执型为多,近期疗效较好。临床症状中有不少项目两组患者也有显著差别,除发病年龄两组间又存在这些显著差异,因此考虑两组是否存在有异质性的可能。
AbstractObjective: To detect the differences between late-onset and non-lateonset schizophrenia. Method:Two hundred and twenty-eight late-onset (>45 years old)schizophrenic patients from 4 mental hospi-tals were compared with 309 non-late-onset schizophrenic inpatients admitted during the same period inthe same hospitals,Result:It showed that late-onset patients had lower educational level,more psycho-logical or physical precipitating factors,more acute ot subacute onset,more neurotic symptoms,lesspersonality change,more frequently paranoid in nature,and a better short-term response to treatment.Discussion:The authors suggested that these findings attested to the heterogeneity of the schizophrenia.
出处
《临床精神医学杂志》
1995年第5期274-276,共3页
Journal of Clinical Psychiatry